Cryonics Magazine- Scientists Eavesdrop Inside the Mind
- Discovery May Provide Insight into Brain Cell Aging
- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
- Fight Aging!
- Chronosphere
- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Tag Archives: Vitrification
Annotated bibliography of cryoprotectant toxicity
Introduction Cryoprotectant toxicity should be distinguished from other mechanisms of cryopreservation injury such as chilling injury (injury produced by too low temperatures as such) and cold shock (injury produced by rapid cooling). Cryoprotectant toxicity itself can again be divided into … Continue reading
Posted in Cryonics, Science
Tagged Brian Wowk, Cryobiology, Cryoprotectant Toxicity, DMSO, Ethylene Glycol, Glycerol, Gregory Fahy, Vitrification
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Intermediate temperature storage in cryonics
The recent issue of Cryonics magazine features a comprehensive update on intermediate temperature storage (ITS). This article contains an important observation: Acoustic events consistent with fracturing were found to be universal during cooling through the cryogenic temperature range. They occurred … Continue reading
Posted in Cryonics
Tagged Alcor, Fracturing, Freezing, Glass Transition Temperature, Intermediate Temperature Storage, Thermal Stress, Vitrification
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The double standard about cryonics
One of the most predictable features of public debates about cryonics is that those arguing in favor of cryonics are held to more rigorous standards than those seeking conventional medical treatment. Advocates of cryonics do not just have to prove … Continue reading
Posted in Cryonics
Tagged Cell Repair, Cryonics, Emergency Medicine, Neurogenomics, Technological Stasis, Vitrification
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The case against cryonics
What is striking about cryonics is that those who have taken serious efforts to understand the arguments in favor of its technical feasibility generally endorse the idea. Those who have not made cryonics arrangements usually give non-technical arguments (anxiety about … Continue reading
Posted in Cryonics, Neuroscience
Tagged Cryonics, Cryonics Criticism, Cryopreservation, Decision Making Under Uncertainty, Decision Theory, Memory, Mike Darwin, Personal Identity, Personal Survival, Vitrification
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Chemical preservation and cryonics research
In the 2009-4 issue of Alcor’s Cryonics magazine I review the technical and practical feasibility of chemical preservation. One of the most interesting aspects of chemopreservation is that it could play a useful role in the cryopreservation of ischemic patients. … Continue reading
Posted in Cryonics, Neuroscience, Science
Tagged Brain Preservation, Chemical Fixation, Chemopreservation, Cryonics, Ischemia, Vitrification
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Ben Best on the feasibility of cryonics at SENS3
Posted in Cryonics, Death, Science
Tagged Arrhenius Equation, Ben Best, Cerebral Ischemia, Cryobiology, Cryonics, Death, Peter Safar, Rejuvenation, SENS, Vitrification
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Cryonics in the media
The Detroit News features a story about cryonics that is a good illustration of the upward battle that cryonics faces in the media. First and foremost, this story reinforces the idea that cryonics concerns the practice of freezing dead people: … Continue reading
The pursuit of cryonics as medicine
The biggest obstacle to the acceptance of cryonics is medical myopia; the idea that someone who has been pronounced dead by contemporary medical criteria will still be considered dead by future criteria. Advocates of human cryopreservation strongly argue against this. … Continue reading
Posted in Cryonics
Tagged Alcor, Bioethics, Critical Care Medicine, Cryobiology, Cryonics, Jerry Leaf, Medical Myopia, Medicine, Mike Darwin, Nanotechnology, Synthetic Biology, Vitrification
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Reversible cryopreservation
On the forum of the Immortality Institute there is an interesting exchange about the feasibility and time line for reversible cryopreservation. Cryobiologist Brian Wowk weighs in with some interesting observations: I think in the next 20 years more small animal … Continue reading
Posted in Cryonics
Tagged Brain Cryopreservation, Brian Wowk, Cryobiology, Cryonics, Ischemia, Nanotechnology, Vitrification
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Basile J. Luyet on the instability of solidified solutions
Basile J. Luyet (1897-1974) can be considered the father of modern cryobiology. His book “Life and Death at Low Temperatures” is a classic in the field and his journal “Biodynamica” evolved into a publication solely dedicated to the study of … Continue reading
Posted in Cryonics, Science
Tagged Basile J. Luyet, Ben Best, Cryobiology, Cryonics, De-vitrification, Greg Fahy, Intermediate Temperature Storage, Low Temperature Biology, Vitrification
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The red blood cell as a model for cryoprotectant toxicity
Various approaches are available to investigate cryoprotectant toxicity, ranging from theoretical work in organic chemistry to cryopreservation of complete animals. Because resuscitation of complex organisms after cryopreservation is not feasible at the moment, such investigations need to be confined to … Continue reading
Posted in Health, Science
Tagged Cryobiology, Cryoenzymology, Cryoprotectant Toxicity, Erythrocytes, Red Blood Cells, Vitrification
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Cryonics sets example for emergency medicine
One of the most neglected aspects of cryonics is that its procedures, and the research to support them, can have important practical applications in mainstream fields such as organ preservation and emergency medicine. Contrary to popular opinion, cryonics does not … Continue reading
Posted in Cryonics, Health
Tagged Cardiac Arrest, CPR, Cryonics, Emergency Medicine, EMS, Hypothermia, Mike Darwin, ResQPOD, Resuscitation, Vitrification
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Famous preserved body parts
The website TopTenz recently published a list of the Top 10 Most Famous Preserved Body Parts. The list includes Galileo’s finger and Albert Einstein’s brain. As has been discussed on this blog before, the preservation of human brains (no matter … Continue reading
Posted in Arts & Living, Death
Tagged Albert Einstein, Benito Mussolini, Boyd Rice, Cryonics, Death, Predappio, Vitrification
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Cryoenzymology and cryoprotectant toxicity
The major limiting obstacle to reversible cryopreservation of complex organs is cryoprotectant toxicity. Elimination of ice formation through vitrification requires high concentrations of cryoprotective agents. These high concentrations of cryoprotectants can be toxic to tissues. Over the years, major advances … Continue reading
Posted in Cryonics, Science
Tagged Astrobiology, Cryobiology, Cryoenzymology, Extremophiles, Vitrification
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Vitrification agents in cryonics
Today’s post on 21st Century Medicine’s vitrification agent M22 completes the series on vitrification agents in cryonics. To date, three different vitrification agents have been used for cryopreservation of humans: B2C (at Alcor from 2001-2005), VM-1 (at the Cryonics Institute … Continue reading
Posted in Cryonics
Tagged Alcor, Cryobiology, Cryonics, Cryonics Institute, Vitrification
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Vitrification agents in cryonics: M22
M22 represents the culmination of decades of work in applied cryobiology by researchers Gregory Fahy , Brian Wowk, and others to develop a vitrification agent that can recover complex organs (such as the kidney) from cryogenic temperatures without ice formation … Continue reading
Posted in Cryonics
Tagged 21st Century Medicine, Brain, Brian Wowk, Cryonics, Cryopreservation, Gregory Fahy, Vitrification
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The first vitrification agent in cryonics: B2C
In 2001 the Alcor Life Extension Foundation licensed its first vitrification agent from the cryobiology research company 21st Century Medicine (21CM) to be used for its neuropatients. The composition of this agent, called B2C, has now been made public on … Continue reading
Why is cryonics so unpopular?
In his 1998 essay “The Failure of the Cryonics Movement” (part 1, part 2), Saul Kent stresses that cryonics has remained so unpopular because nobody thinks it will work. One observable implication of this view is that we would expect … Continue reading
Posted in Cryonics, Death
Tagged Critical Care Medicine, Cryonics, Fear of Death, Life Extension, Vitrification
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Cryoprotectant toxicity: biochemical or osmotic?
The current generation of vitrification agents in cryonics permit elimination of ice formation using realistic cooling rates. But attempts to vitrify the brain require high concentrations of cryoprotective agents to inhibit ice formation. Such high concentrations of cryoprotectants can produce … Continue reading
Posted in Cryonics
Tagged Cryobiology, Cryonics, Cryoprotectant Toxicity, Vitrification
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Viability in brain cryopreservation
Because the current generation of vitrification agents permit cryopreservation of the brain without ice formation, the current objective of cryonics research is maintenance of viability of the brain during cryopreservation. The most popular viability assay that has been used in … Continue reading
Posted in Cryonics, Neuroscience
Tagged 21st Century Medicine, Cryobiology, Cryonics, Cryopreservation, Memory, Viability Assays, Vitrification
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Ben Best publishes on cryonics in Rejuvenation Research
A technical cryonics article to be published in the conference proceedings of a customarily peer-reviewed scientific journal, entitled “Scientific Justification of Cryonics Practice (pdf),” by Ben Best, President of the Cryonics Institute, will appear in the next issue (Volume 11, … Continue reading
Posted in Cryonics, Science
Tagged Ben Best, Cryobiology, Cryonics, Rejuvenation, Vitrification
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