Depressed Metabolism

One of the most common criticisms of cryonics is to argue that cryonics can only be a legitimate endeavor when there is (peer reviewed) demonstration of whole body suspended animation. Advocates of cryonics  point out that this is an unreasonable position because it sets a standard for rational decision making (certainty) that is rarely encountered, [...]

This past weekend (Friday, January 8, 2010 to Sunday, January 10, 2010) I attended a meeting for cryonicists in their teens & twenties near Fort Lauderdale, Florida. The event was funded by Bill Faloon and the Life Extension Foundation. Cairn Idun, creator & coordinator of the Asset Preservation Group, created & coordinated this event as [...]

The Detroit News features a story about cryonics that is a good illustration of the upward battle that cryonics faces in the media. First and foremost, this story reinforces the idea that cryonics concerns the practice of freezing dead people:
Preparation of the body is a five-day procedure. It begins with keeping the body as cool [...]

If conventional cardiopulmonary support (CPS) in cryonics is difficult to perform adequately, and impossible to sustain for more than brief periods (30-60 min) before exhausting even a 3-man standby team, this is even more the case for active compression-decompression CPS (ACD-CPS) using the ResQPump (formerly the Ambu CardioPump). Even in the conventional medical setting of [...]

Cryonics patients can greatly benefit from rapid stabilization after pronouncement of legal death. One fortunate feature of stabilization procedures is that the most effective and validated procedures are relatively inexpensive and easy to perform.  The difference between no stabilization procedures at all and procedures that aim to rapidly restore blood circulation and drop the patient’s [...]

Esquire magazine features an article on scientist Mark Roth and his research into “suspended animation.” As the website title “The Mad Scientist Bringing Back the Dead…. Really” indicates, this is not supposed to be a detailed account of Ikaria’s recent advances in induction of depressed metabolism but a sensationalist piece on mad scientists. Although the [...]

Recent advances with the use of hydrogen sulfide, carbon monoxide and “hibernation induction triggers” to depress metabolism in animal models have  renewed interest  in the possibility of human hibernation.  The ability to drastically depress human metabolism without the use of cold (or in combination with cold) would have a number of important medical and scientific [...]

Can life exist without water? This is one of the questions that fascinates astrobiologists. The behavior of biomolecules in non-aqueous solutions is also of interest to cryobiologists and cryoenzymologists. Ice formation below zero degrees Celsius can be prevented by high concentrations of cryoprotective agents. But what are the effects of such vitrification agents on proteins?
In [...]

Now online is an old interview with Robert W. Prehoda. Prehoda was a prolific science writer who published on topics such as aging, life extension, and technological forecasting. In 1969 Prehoda published the book “Suspended Animation: The Research Possibility That May Allow Man to Conquer the Limiting Chains of Time.” In this visionary book, Prehoda [...]

On the Immortality Institute cryonics forum, Alcor Board member and researcher Brian Wowk has posted some insightful comments on the difference between suspended animation and cryonics. Although  impressive technical advances in cryonics to date, such as vitrification, have failed to translate into increased membership growth for cryonics organizations, many cryonics observers believe that demonstration of [...]

“Cryonics does not involve the freezing of dead people. Cryonics involves placing critically ill patients that cannot be treated with contemporary medical technologies in a state of long-term low temperature care to preserve the person until a time when treatments might be available.”
Read the complete article here.

In a widely publicized series of experiments by Blackstone et al., hydrogen sulfide (H2S) was found to induce hypometabolism in mice. These experiments raised interest in whether such “suspended animation” could be achieved in humans. If administration of H2S would be able to reduce metabolic rate in humans to the same extent as observed in [...]