Cryonics Magazine- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
- Messenger RNA Self-destruct Mechanism Revealed
- How the Brain Cell Works: A Dive Into Its Inner Network
- Fight Aging!
- Chronosphere
- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Tag Archives: Stroke
How many neurons need to survive for cryonics to work?
On this page a calculation is attempted to determine how many neurons need to survive for cryonics to work. The flaw in this approach should be obvious when the author writes : According to The Stroke Association, a stroke is … Continue reading
Posted in Cryonics
Tagged Alcor, Cell Death, Cerebral Ischemia, Cryonics, Delayed Neuronal Death, Nanomedicine, Stroke
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The science of personal survival
There are various competing strategies how to achieve meaningful life extension or rejuvenation, including , but not limited to, genetic manipulation, periodical elimination of damage, caloric restriction, molecular nanotechnology and mind uploading. A useful review of these strategies has been … Continue reading
Posted in Cryonics, Death, Science
Tagged Anti-Aging, Biotechnology, Cryonics, Inductivism, Longevity Science, Mind Uploading, Molecular Nanotechnology, Nassim Nicholas Taleb, Personal Survival, Rejuvenation, Research, Rudolf Carnap, Stroke
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Gender differences in stroke treatment and prevention
Over the years, experimental science has developed a standard protocol for the testing of medical hypotheses using animal models which calls for the use of males only. Why? Because no laboratory scientist wants to deal with those pesky female hormones. … Continue reading
The chemistry of neuroprotection
In a review of the 1998 21st Century Medicine seminars, Cryonics Institute president Ben Best writes: “The presentations impressed upon me how much witchcraft and how little science has gone into the study of cryoprotectant agents (CPAs). This might be … Continue reading
Posted in Neuroscience
Tagged Cardiac Arrest, Cerebral Ischemia, Drugs, Neuroprotection, Peter Safar, Stroke
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Dietary supplements induce neurogenesis after stroke
A recent study in Rejuvenation Research reports that a combination of dietary supplements confer neuroprotection in stroke. Over a 2 week period rats received either a proprietary formulation of blueberry, green tea, Vitamin D3, and carnosine called NT-020 or vehicle … Continue reading
Posted in Health, Neuroscience
Tagged Blueberry, Ischemia, Neuroprotection, NT-020, Stroke
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Critical cooling rate to prevent ischemic brain injury
Induction of hypothermia can reduce injury to the brain when it is deprived of oxygen. How fast do we need to cool a patient during cardiac arrest or stroke to prevent irreversible injury to the brain? It is an established … Continue reading
Posted in Cryonics, Neuroscience
Tagged Cardiac Arrest, Cerebral Ischemia, Cryonics, Hypothermia, Neuroprotection, Stroke
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Cerebral ischemia and impairment of circulation
Cryopreservation of the brain depends on the removal of blood from the brain’s vasculature and its replacement with cryoprotective solutions in order to prevent ice crystal formation (freezing) during cooling (i.e., facilitate vitrification). Ultimately, the success of a good cryoprotectant … Continue reading
Posted in Cryonics, Neuroscience
Tagged Blood Coagulation, Cardiac Arrest, Cryonics, Heparin, Stroke
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Wide therapeutic window for melatonin in stroke
Neuroprotective agents for stroke continue to fail in clinical trials. One important reason is that the therapeutic window for many of those agents is too narrow to confer benefits to acute stroke victims. It would be desirable to have a … Continue reading
Posted in Cryonics, Health, Neuroscience
Tagged Cerebral Ischemia, Cryonics, Melatonin, Stroke
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Preventing vegetative patients through cryonics
The blog Practical Ethics reports on pioneering research from a group of scientists in Cambridge who are using fMRI scans to study the brains of people who have been diagnosed as being in a vegetative condition. A Persistent Vegetative State … Continue reading
Posted in Cryonics, Neuroscience
Tagged Cardiac Arrest, Cryonics, Persistent Vegetative State, Stroke, Terri Schiavo
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Neuroprotection for ischemic stroke
The journal Neuropharmacology recently published a new review of the current state of the art in neuroprotection for ischemic stroke. A strict definition of a neuroprotectant excludes agents that have as their goal circulatory patency or the reversal of vascular … Continue reading
Posted in Cryonics, Neuroscience
Tagged Clinical Trials, Ischemia, Neuroprotectant, Stroke, tPA
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Incomplete assessment of experimental cytoprotectants in rodent ischemia studies
In an effort to determine why so many cytoprotective treatments for stroke that are shown to be promising in laboratory animal experiments ultimately fail in human clinical trials, DeBow et al. performed an analysis of cytoprotection studies published in several … Continue reading
Posted in Neuroscience
Tagged Animal Research, Neuroprotectant, Research, Rodents, Science, Stroke
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Systemic administration of L-Kynurenine
L-Kynurenine (L-KYN) is one of the neuroprotective agents used in cryonics stabilization protocol to limit injury to the brain after cardiac arrest. Administration of L-KYN was perceived to be essential to resuscitate dogs from extended periods (up to 17 minutes) … Continue reading
Posted in Cryonics, Neuroscience
Tagged Blood Pressure, Hemodynamics, Ischemia, Kynurenine, Neuroprotectant, Stroke
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Fever and brain injury
Elevation of body temperature occurring as a result of hypothalamic coordination of autonomic, neuroendocrine, and behavioral responses in reaction to physiological injury or invasion is generally known as fever. Traditional thought is that the “febrile response” is beneficial in preventing … Continue reading
Posted in Neuroscience
Tagged Brain, Hyperthermia, Hypothermia, Ischemia, Stroke, Temperature
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Combination therapy: The patient’s view
One consequence of the growing understanding of the biochemical pathways involved in brain injury resulting from cardiac arrest, stroke, and brain trauma is that there is an increasing consensus among researchers that combination therapy is the most logical treatment for … Continue reading
Posted in Cryonics, Health
Tagged Cancer, Cardiac Arrest, Drug Cocktail, NXY-059, Stroke
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Leukocytes and cerebral ischemia
In their paper “The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct?” D.F. Emerich et al. review the literature on the involvement of neutrophils in cerebral ischemia: “We reasoned that if neutrophils play an … Continue reading
Posted in Cryonics, Neuroscience
Tagged Inflammation, Leukocytes, Necrosis, Neutrophils, Stroke
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