Selection bias and dietary supplements
One problem in assessing the merits of taking a specific dietary supplement (ranging from vitamins to exotic multi-ingredient compounds) is widespread selection bias in the documentation that is supposed to support the use of the supplement in question. The sheer number of scientific studies combined with variation in research methodologies virtually guarantees that for every [...]
Albert Einstein’s brain and information-theoretic death
“People like you and I, though mortal of course like everyone else, do not grow old no matter how long we live…[We] never cease to stand like curious children before the great mystery into which we were born.”
Albert Einstein
One sign of the lack of faith in the future progress of technology and the poor acceptance [...]
Incomplete assessment of experimental cytoprotectants in rodent ischemia studies
In an effort to determine why so many cytoprotective treatments for stroke that are shown to be promising in laboratory animal experiments ultimately fail in human clinical trials, DeBow et al. performed an analysis of cytoprotection studies published in several leading journals. While noting that limitations in preclinical assessments also contribute to the premature advancement [...]