Promoting cerebral blood flow in cryonics patients
It has been shown that perfusability of the brain is significantly compromised after long-term (>5 min) ischemic events (the “no reflow” phenomenon). Improving cerebral blood flow after circulatory arrest is one of the fundamental objectives of human cryopreservation stabilization protocol. To that end, cryonics organizations administer the resuscitation fluid Dextran-40 and the drug Streptokinase to [...]
Intranasal administration of medications
Experiments investigating the effects of medication administration via the nose are becoming increasingly common in scientific literature. Direct olfactory transport to the brain and the consequent lack of systemic side effects make nasal administration of neuroactive drugs a very attractive option for doctors and patients alike.
Neuropeptides such as insulin and melanocortins are known to play [...]
Human cryopreservation combinational pharmacotherapy
A comprehensive review of cryonics stabilization medications is now published on the Alcor website.
Table of contents:
* Introduction
* General Anesthesia
* Blood Coagulation
* Vasoactive Medications
* Excitotoxity
* Free Radicals
* Nitric Oxide and PARP
* Inflammation
* Antibiotics
* Acidosis
* Hemodilution and Osmotic Therapy
* Coenzyme Q10
* Magnesium
* Na+ /H+ Exchange Inhibition
* Immunosuppressive Drugs
* Gastrointestinal Ischemia
* Depressed Metabolism
* Combining Medications
* Conclusion