Tag Archives: Brain

Vitrification agents in cryonics: M22

M22 represents the culmination of decades of work in applied cryobiology by researchers Gregory Fahy , Brian Wowk, and others to develop a vitrification agent that can recover complex organs (such as the kidney) from cryogenic temperatures without ice formation … Continue reading

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Cerebral blood flow during and after cardiac arrest

As discussed in a previous post, perfusion of the brain following long-term (>5 min) ischemia has been shown to be significantly compromised, particularly in subcortical regions. An interesting recent article by Ristagno, et. al in Resuscitation (May 2008) has added … Continue reading

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Albert Einstein’s brain and information-theoretic death

“People like you and I, though mortal of course like everyone else, do not grow old no matter how long we live…[We] never cease to stand like curious children before the great mystery into which we were born.” Albert Einstein … Continue reading

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Fever and brain injury

Elevation of body temperature occurring as a result of hypothalamic coordination of autonomic, neuroendocrine, and behavioral responses in reaction to physiological injury or invasion is generally known as fever. Traditional thought is that the “febrile response” is beneficial in preventing … Continue reading

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In situ chemical fixation of whale brains

As discussed by R. Michael Perry in his recent contribution to Cryonics Magazine, “Alternatives to Cryonics: A Very Preliminary Study,” (3rd Quarter 2007) chemical fixation of the brain may be a substitute for cryopreservation in circumstances where cryonics is not … Continue reading

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Characterization of afterhyperpolarization (AHP) in cryopreserved brain slices

An ongoing quest in cryonics is the successful demonstration of memory sustainment after cryopreservation of the brain and rewarming from cryogenic temperatures. To that end, landmark experiments were performed by Pichugin, et al. (2006) on rat hippocampal brain slices which … Continue reading

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Whole body cryopreservation with preferential brain treatment

A strong argument in favor of neuropreservation is that all efforts can be devoted to vitrification of the brain. Perfusion times are shorter and challenges present during perfusion of the rest of the body (such as abdominal swelling and the … Continue reading

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