Tag Archives: Brain Aging

ApoE4 – The Ancestral Allele

Posted on August 5, 2011 by Aschwin de Wolf

Reportedly, when James Watson and Steven Pinker had their genome sequenced, they declined to know their risk for Alzheimer’s disease. Clearly this is not an option for life extensionists and cryonicists, who are better off knowing whether they have a copy … Continue reading →

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TNF-alpha modulation in Alzheimer’s patients

Posted on July 27, 2008 by Chana de Wolf

More than a decade of basic research and clinical evidence now implicates inflammatory processes in the pathogenesis of Alzheimer’s disease (AD). TNF-alpha is a pro-inflammatory cytokine, also known as the “master regulator” of the immune response, and is the key … Continue reading →

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Enbrel reverses Alzheimer’s cognitive deficits

Posted on July 13, 2008 by Aschwin de Wolf

The latest issue of Life Extension Magazine (August 2008) contains an encouraging report about off-label use of etanercept (commercial name: Enbrel) to reverse the cognitive deficits associated with Alzheimer’s disease. Etanercept is a tumor necrosis factor (TNF) blocker that is … Continue reading →

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