Depressed Metabolism

This is the eighth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. In 1982, P.D. Rogers and G.P. Webb published some of their observations (based on previous papers and a Ph.D thesis) after carrying out a classroom demonstration of suspended animation in which they [...]

This is the seventh entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. After spending a few years on perfecting on Andjus’ technique for resuscitating rodents (rats and hamsters) from ultraprofound hypothermic and high subzero temperatures, Audrey Smith upped the ante and attempted the same [...]

This is the fifth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. As we have seen, Radoslav Andjus had determined a method for achieving excellent (75-100%) recovery rates in rats cooled to 0-2 degrees C by local cardiac heating prior to warming the whole [...]

This is the fourth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. Up to this point we have discussed the groundbreaking research in the early 1950s performed by Radoslav Andjus in resuscitating rats from body temperatures between 0 and 2 degrees C. Having determined [...]

This is the second entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. As discussed previously, in 1951 Radoslav Andjus developed a simple method for resuscitating rats cooled to deep body temperatures between 0 and 2 degrees C which involved applying a hot spatula to [...]

This is the first entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. Prior work in hypothermia began in the early 1900s, but because cardiac and respiratory arrest were observed in the animals around 15 degrees C, researchers assumed they were irreversibly dead [...]