Category Archives: Science

Annotated bibliography of cryoprotectant toxicity

Introduction Cryoprotectant toxicity should be distinguished from other mechanisms of cryopreservation injury such as chilling injury (injury produced by too low temperatures as such) and cold shock  (injury produced by rapid cooling). Cryoprotectant toxicity itself can again be divided into … Continue reading

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The 2011 Cryobiology Conference

July 24-27 I attended the 2011 annual Society for Cryobiology conference in Corvallis, Oregon. A number of the first presentations were concerned with means to *avoid* cryopreservation. Room temperature storage is much less expensive and troublesome, and improves ease of … Continue reading

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The Future of Aging: Pathways to Human Life Extension

This book review was originally published in Cryonics magazine, 1st Quarter, 2011. Editor-in-chief, cryobiologist, and aging researcher Gregory M. Fahy and his associate editors Michael D. West, L. Stephen Cole and Steven B. Harris have compiled what might be the … Continue reading

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Philosophy of science and life extension

Paul Edwards concludes his chapter ‘The Semantic Challenge’ in his book God and the Philosophers with the following observation about logical positivism: It is not uncommon nowadays to hear logical positivism dismissed as a set of crude errors and confusions. … Continue reading

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The RhinoChill: A New Way to Cool the Brain Quickly

We scientists are difficult, cranky, and above all, maddeningly frustrating people. Want to turn lead into gold? No problem, we can tell you how to do that, and in fact have even done it already: the only catch is that … Continue reading

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Prospects for Mild Therapeutic Hypothermia and Improved CPR in Cardiopulmonary Cerebral Resuscitation

There are two kinds of hypothermia: protective or preservative hypothermia, and therapeutic hypothermia. The former is easy and straightforward to understand for most, clinicians and laymen, alike.  However, therapeutic hypothermia has proved to be a far more difficult idea to … Continue reading

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Suspended Animation Conference 2011

The cryonics company Suspended Animation “will sponsor the conference, “Suspended Animation – The Company and The Goal,” which will be held in Fort Lauderdale in May, 2011. The conference will feature speakers on the latest strategies and advances toward perfecting … Continue reading

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Is a life worth starting? Some personal views

For life—the life of any sentient creature—to be worth living, there must, as Robert Ettinger has often said, be a preponderance of satisfaction over dissatisfaction. If this overall slant toward good rather than bad is maintained, it seems reasonable that … Continue reading

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Non-existence is hard to do

A review of  contemporary antinatalist writings Originally published in Cryonics, 2nd Quarter, 2010 (PDF) “Coming into existence is bad in part because it invariably leads to the harm of ceasing to exist.” David Benatar “If they could get a corpse … Continue reading

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At last, a sure-cold way to sell cryonics with guaranteed success!

A humorous romp through a promising new technique in aesthetic medicine from one cryonicist’s (warped) point of view. Figure 1: Before cryopreservation (L) and after cryopreservation (R). As everyone involved in cryonics for more than a fortnight is sadly aware, … Continue reading

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The diminishing returns of reactive medicine

In an article for Slate, Jay Olshansky argues in favor of a position that one would expect to be common sense at this point: While we can extend life in aging bodies through behavioral improvements and medical treatments, the time … Continue reading

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Meta-research and medical skepticism

The Atlantic features an important article about “meta-researcher” Athina Tatsioni, who has published a number of influential papers about the quality of biomedical research: He and his team have shown, again and again, and in many different ways, that much … Continue reading

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October 2010 Cryonics Symposium in Germany

On the first weekend of October, 2010 I was an invited speaker at “Applied Cryobiology – Scientific Symposium on Cryonics” held in Goslar, Germany: http://www.biostase.de/us/symposium2010.html. The meeting was the first effort by the German Society for Applied Biostasis (DGAB) to … Continue reading

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Thought experiments as knowledge

One of the most remarkable aspects about the ongoing debates concerning the technical feasibility of mind uploading is the excessive confidence that some people have that these issues can be resolved without further experimental validation. The (implicit) assumption seems to … Continue reading

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David J. Chalmers on the Singularity, mind uploading and cryonics

If I would make an argument in favor of mind uploading (or substrate independent minds) it would not be a logical deduction from what we know about neuroscience but from what we don’t know.  As one of the leading philosophers … Continue reading

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Edward O. Wilson’s Consilience

Sociobiologist Edward O. Wilson believes that a major reason why the social sciences have made so little progress is that its practitioners have ignored the biological basis of human behavior. He is not impressed with arguments that purport that the … Continue reading

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The low-hanging fruit of technological progress

The website Alternative Right has an interesting article on the declining pace of technological progress: The world of 1959 is pretty much the same world we live in today technologically speaking. This is a vaguely horrifying fact which is little … Continue reading

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Free will versus determinism as it relates to cryonics

Excerpt from “Ben Best – A Case for Free Will AND Determinism” Determinism implies materialism — implies that consciousness is material. Cryonics is based on the premise that the preservation of the fine structure of the brain at low temperature … Continue reading

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Chemical preservation and cryonics research

In the 2009-4 issue of Alcor’s Cryonics magazine I review the technical and practical feasibility of chemical preservation. One of the most interesting aspects of chemopreservation is that it could play a useful role in the cryopreservation of ischemic patients. … Continue reading

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Cryonics Oregon june meeting report

About 35 people attended the Cryonics Oregon-sponsored debate on the subject of SENS. Chana de Wolf was mistress of ceremonies. A show of hands indicated that the great majority of those attending were signed-up cryonicists. There was a sizeable contingent … Continue reading

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Cryonics Oregon June Meeting with Aubrey de Grey and Ben Best

On June 6th the next Cryonics Oregon meeting will coincide with a downtown Portland aging conference. As a result we have been successful in persuading Cryonics Institute President Ben Best and Alcor member and biogerontologist Aubrey de Grey to attend … Continue reading

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Down with uploading

Over the last couple of years, cryonics pioneer Robert Ettinger has been a vocal critic of simplistic defenses of the idea of mind uploading as a survival strategy. He has worked out his reservations in detail in his latest book … Continue reading

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The theological orientation of philosophy

In spite of the empiricist trend of modern science, the quest for certainty, a product of the theological orientation of philosophy, still survives in the assertion that some general truths about the future must be known if scientific predictions are … Continue reading

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Ben Best on the feasibility of cryonics at SENS3

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Biological enhancement and evolution

In the March 2010 issue of Reason magazine Tim Cavanaugh writes about the rift between transhumanists who favor biological enhancement versus those who favor non-biological “mechanical” enhancement: These days transhumanists talk a lot about subcutaneous data ports, permanent immersion in … Continue reading

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The science of personal survival

There are various competing strategies how to achieve meaningful life extension or rejuvenation, including , but not limited to, genetic manipulation, periodical elimination of damage, caloric restriction,  molecular nanotechnology and mind uploading. A useful review of these strategies has been … Continue reading

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Hans Reichenbach on empiricism

“The crisis of empiricism, expressed in David Hume’s scepticism, was the product of a misinterpretation of knowledge and vanishes for a correct interpretation – such is the outcome of a philosophy grown from the soil of modern science. The rationalist … Continue reading

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Radio interview with Cryonics Institute President Ben Best

Cryonics Institute President Ben Best talks about cryonics and how cryonics is related to rejuvenation in this one-hour long interview on “It’s Rainmaking Time!” Further Reading: Depressed Metabolism Interview with Ben Best

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Peter Thiel: Utopian Pessimist

Peter Thiel, one of the few original minds in the life extension and accelerating-technological-change community, is featured in a short interview at Wired. Thiel seems to be aware of the limitations of extrapolation of trends: We’ve been living in a … Continue reading

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Scientific consensus

Scientific consensus seems a reasonable concept. If a great number of individual scientists arrive at a similar opinion this is generally a sufficient reason to have confidence in those views. Skeptics about scientific consensus often use examples of scientific views … Continue reading

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The singularity is not near

Singularity skeptic Mark Plus drew my attention to the following blog post. The author writes that: Chalmers’ (and other advocates of the possibility of a Singularity) argument starts off with the simple observation that machines have gained computing power at … Continue reading

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The 2009 SENS Conference

Once a year I try to attend at least one biogerontology conference. Although I attend biogerontology conferences out of personal interest, and at my own expense, they are the most fruitful grounds for promoting cryonics I have found, and this … Continue reading

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Revival of cryonics patients literature

There is a growing literature that discusses the technical aspects of revival of cryonics patients. The following list of the published literature was compiled by Ralph Merkle and Robert Freitas and published as an appendix of their article on molecular … Continue reading

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Stuart Gordon’s Re-Animator and the science of cryonics

This past weekend Motel X, the Lisbon (Portugal) International Horror festival, had its third anniversary. It is one of the smaller international horror festivals around, but this year they managed to have both Stuart Gordon, director of several Lovecraft adaptions, … Continue reading

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Karl Popper and Rudolf Carnap revisited

In his classic book Significance and Basic Postulates of Economic Theory (1938) Terence W. Hutchison  makes the case for economics as an empirical science. An interesting aspect about this book is the ease with which Terence W. Hutchison uses logical … Continue reading

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