Archive for the 'Hibernation' Category

Human cryopreservation combinational pharmacotherapy

Wednesday, November 28th, 2007

A comprehensive review of cryonics stabilization medications is now published on the Alcor website.
Table of contents:
* Introduction
* General Anesthesia
* Blood Coagulation
* Vasoactive Medications
* Excitotoxity
* Free Radicals
* Nitric Oxide and PARP
* Inflammation
* Antibiotics
* Acidosis
* Hemodilution and Osmotic Therapy
* Coenzyme Q10
* Magnesium
* Na+ /H+ Exchange Inhibition
* Immunosuppressive Drugs
* Gastrointestinal Ischemia
* Depressed Metabolism
* Combining Medications
* Conclusion
If you enjoyed [...]

Hydrogen sulfide does not induce hypometabolism in sheep

Monday, November 12th, 2007

In a widely publicized series of experiments by Blackstone et al., hydrogen sulfide (H2S) was found to induce hypometabolism in mice. These experiments raised interest in whether such “suspended animation” could be achieved in humans. If administration of H2S would be able to reduce metabolic rate in humans to the same extent as observed in [...]

Energy metabolism and sepsis

Thursday, September 6th, 2007

In this recent paper the authors argue that “multi-organ failure secondary to sepsis may actually represent an adaptive hypometabolic response to preserve ATP homeostasis in the face of a prolonged inflammatory insult.” Unlike organ specific diseases, mitochondrial dysfunction in multiple organ failure may be potentially reversible by careful timing of proper treatment. The authors warn [...]