Cryonics Magazine- Scientists Eavesdrop Inside the Mind
- Discovery May Provide Insight into Brain Cell Aging
- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
- Fight Aging!
- Chronosphere
- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Category Archives: Health
The 2011 Calorie Restriction Society Conference
On October 27-29 I attended CR VII, the 2011 Calorie Restriction Society Conference held in Las Vegas, Nevada. Members of the Calorie Restriction Society restrict their calories while maintaining adequate nutrition as a means of extending their lifespan (or improving … Continue reading
Posted in Cryonics, Health
Tagged Ben Best, Brenda Peters, Caloric Restriction, Calorie Restriction, Calorie Restriction Society, Cryonics, Luigi Fontana, Peter Voss, Shannon Vyff, Stephen Spindler
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What you don’t eat can’t hurt you
Many people in the life extension community follow some kind of diet. Historically, caloric restriction (CR) has been the most popular and most discussed option. Other popular diets include the Mediterranean diet and the Paleolithic diet. In one sense, comparing … Continue reading
Posted in Cryonics, Health, Personal Genomics
Tagged Alzheimer's Disease, ApoE4, Caloric Restriction, Cryonics, Evolution, Genotype, Mediterranean Diet, Neurodegenerative Diseases, Nutrigenetics, Paleolithic Diet, Saturated Fat, The 10000 Year Explosion
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Smartphone Apps for the Smart Cryonicist
As every modern consumer knows, smartphones are today’s go-to portable technology. Everything from GPS navigation to finding a good deal on your next meal or haircut right NOW to a wide variety of games and applications may be had at … Continue reading
Posted in Cryonics, Health
Tagged apps, Cryonics, Health, mobile technology, smartphone
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ApoE4 – The Ancestral Allele
Reportedly, when James Watson and Steven Pinker had their genome sequenced, they declined to know their risk for Alzheimer’s disease. Clearly this is not an option for life extensionists and cryonicists, who are better off knowing whether they have a copy … Continue reading
Posted in Health, Neuroscience, Personal Genomics
Tagged 23andMe, Alcor, Alzheimer's Disease, ApoE4, Brain Aging, Cryonics, Life Extension, Paleo Diet, Patri Friedman
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At last, a sure-cold way to sell cryonics with guaranteed success!
A humorous romp through a promising new technique in aesthetic medicine from one cryonicist’s (warped) point of view. Figure 1: Before cryopreservation (L) and after cryopreservation (R). As everyone involved in cryonics for more than a fortnight is sadly aware, … Continue reading
Posted in Cryonics, Health, Science
Tagged Adipocytes, Chilling Injury, Cosmetic Surgery, Cryobiology, Cryolipolysis, Cryonics, Hypothermia, Mike Darwin, Organ Preservation, Zeltiq
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Meta-research and medical skepticism
The Atlantic features an important article about “meta-researcher” Athina Tatsioni, who has published a number of influential papers about the quality of biomedical research: He and his team have shown, again and again, and in many different ways, that much … Continue reading
Posted in Health, Science
Tagged 21st Century Medicine, Athina Tatsioni, Cryonics, Michael Anissimov, Research
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Ben Best on nuclear DNA damage and aging
The June 2009 issue of Rejuvenation Research features an article by Cryonics Insitute President Ben Best about the involvement of nuclear DNA damage in the aging process: Abstract This paper presents evidence that damage to nuclear DNA (nDNA) is a … Continue reading
Posted in Health, Science
Tagged Aging, Ben Best, Biogerontology, Cellular Senescence, Cryonics Institute, Nuclear DNA, Rejuvenation, Rejuvenation Research
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CPR and the breath of death?
And the Lord God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul. Genesis 2:7 For breath is life, and if you breathe well you will … Continue reading
Posted in Cryonics, Health, Science
Tagged Active Compression Decompression CPR, Autopulse, CPR, Cryonics, LUCAS, LUCAS 2, Mechanical CPR, Michigan Thumper, Mike Darwin, Negative Pressure Ventilation
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Buried alive?
According to this news item the Alcor Life Extension Foundation is taking legal action against the brother and sister of an Alcor member who “denied the foundation’s request for his body and didn’t notify them of their brother’s death until … Continue reading
Posted in Cryonics, Health
Tagged Alcor, CryoCare, Cryonics, Durable Power of Attorney for Health Care, Hostile Relatives, Living Will
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The red blood cell as a model for cryoprotectant toxicity
Various approaches are available to investigate cryoprotectant toxicity, ranging from theoretical work in organic chemistry to cryopreservation of complete animals. Because resuscitation of complex organisms after cryopreservation is not feasible at the moment, such investigations need to be confined to … Continue reading
Posted in Health, Science
Tagged Cryobiology, Cryoenzymology, Cryoprotectant Toxicity, Erythrocytes, Red Blood Cells, Vitrification
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A simple method to resuscitate rats from cold circulatory arrest
This is the eighth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. In 1982, P.D. Rogers and G.P. Webb published some of their observations (based on previous papers and … Continue reading
Posted in Death, Health, Neuroscience, Science
Tagged Audrey Smith, Death, Hypothermia, Hypoxia, Radoslav Andjus, Ultra-Profound Hypothermia
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The healthy skeptic
Consumers are constantly bombarded with advice about health. Lower your cholesterol, avoid carbs, take dietary supplements, avoid Teflon, get a full body scan, etc. Such advice does not fall on deaf ears. Who does not want to remain healthy, look … Continue reading
Posted in Health, Science
Tagged Dietary Supplements, Health, Life Extension, Meliorism, Science, Skepticism
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Robert Freitas discusses the future of nanomedicine
Nanotechnology idea-man Robert Freitas, Jr. has published an article in the January 2009 issue of Life Extension Magazine providing a tutorial in nanomedicine and documenting its progression toward real-world application. In “Nanotechnology and Radically Extended Life Span,” Freitas describes several … Continue reading
Gender differences in stroke treatment and prevention
Over the years, experimental science has developed a standard protocol for the testing of medical hypotheses using animal models which calls for the use of males only. Why? Because no laboratory scientist wants to deal with those pesky female hormones. … Continue reading
Cryonics sets example for emergency medicine
One of the most neglected aspects of cryonics is that its procedures, and the research to support them, can have important practical applications in mainstream fields such as organ preservation and emergency medicine. Contrary to popular opinion, cryonics does not … Continue reading
Posted in Cryonics, Health
Tagged Cardiac Arrest, CPR, Cryonics, Emergency Medicine, EMS, Hypothermia, Mike Darwin, ResQPOD, Resuscitation, Vitrification
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Help Kronos’ Chris Heward fight his cancer
Chris Heward past away on January 10, 2009. This post will remain here to remember Chris and his struggle against cancer. John Schloendorn, who is a postdoc at ASU’s Biodesign Institute and doing scientific research on the LysoSENS project for … Continue reading
BioTime’s quest to defeat aging
Unless you are a long-time cryonicist or a surgeon, you may not have heard of BioTime before. This company, recently profiled for its innovative stem cell research in Life Extension Magazine, is best known for producing the blood-volume expander Hextend, … Continue reading
PLAC blood test for sudden cardiac arrest and stroke risk
Life Extension Foundation (LEF) unveiled a new blood test in an article in this month’s Life Extension Magazine (November 2008). Unlike cholesterol testing, which simply gives a measurement of high-density (HDL) and low-density (LDL) lipoprotein levels and provides little information … Continue reading
Posted in Health, Science
Tagged Blood Testing, Cardiac Arrest, Health, Ischemia, Life Extension Foundation, PLAC, Science
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Antioxidant skepticism
At the blog Fight Aging!, Reason draws attention to the possibility that taking large amounts of antioxidant supplements may not necessarily be an improvement: Our biology is complex – why would we expect that successfully modifying it with chemicals would … Continue reading
Posted in Health, Science
Tagged Aging, Antioxidants, Free Radicals, Nanomedicine, PBN, Steve Harris
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No disease in the brain of a 115-year old woman
In August 2008, Neurobiology of Aging published the interesting observations of den Dunnen, et al. of the post-mortem body of a 115 year old woman, which showed no evidence of atherosclerosis. Her brain was devoid of the amyloid plaques characteristic … Continue reading
Dietary supplements induce neurogenesis after stroke
A recent study in Rejuvenation Research reports that a combination of dietary supplements confer neuroprotection in stroke. Over a 2 week period rats received either a proprietary formulation of blueberry, green tea, Vitamin D3, and carnosine called NT-020 or vehicle … Continue reading
Posted in Health, Neuroscience
Tagged Blueberry, Ischemia, Neuroprotection, NT-020, Stroke
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Revitalize aging feet
My mother, being a decidedly well put-together woman, impressed upon me the importance of self-care from an early age. She was obsessed with skin maintenance and especially careful to instruct me in hand and foot care. I was given my first bottle … Continue reading
Posted in Health
Tagged Eucalyptus, Flat Feet, Foot care, Health, Life Extension Foundation
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Recent developments in the treatment of Alzheimer’s
The full text of the Life Extension Foundation magazine article (August 2008) describing the use of Enbrel for the treatment of Alzheimer’s disease and announcing LEF’s new Enbrel trial, is now available. As previously discussed, Enbrel (entanercept) has been shown … Continue reading
Posted in Health, Neuroscience
Tagged Aging, Alzheimer's Disease, Drugs, Life Extension Foundation
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TNF-alpha modulation in Alzheimer’s patients
More than a decade of basic research and clinical evidence now implicates inflammatory processes in the pathogenesis of Alzheimer’s disease (AD). TNF-alpha is a pro-inflammatory cytokine, also known as the “master regulator” of the immune response, and is the key … Continue reading
Gary Taubes and bias in nutrition science
In a recent blog post, Overcoming Bias reports that Gary Taubes, who has written much to further the idea that refined carbohydrates are a stronger contributing factor to overweight and “diseases of civilization” than dietary fat and cholesterol, has compiled … Continue reading
Cryonics as an elective medical procedure
The two most popular technical arguments against human cryopreservation are that cryonics causes irreversible freezing damage and that the delay between pronouncement of legal death and the start of cryonics procedures causes irreversible injury to the brain. Such arguments can … Continue reading
Posted in Cryonics, Death, Health
Tagged Critical Care Medicine, Cryonics, Death, Emergency Medicine
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Enbrel reverses Alzheimer’s cognitive deficits
The latest issue of Life Extension Magazine (August 2008) contains an encouraging report about off-label use of etanercept (commercial name: Enbrel) to reverse the cognitive deficits associated with Alzheimer’s disease. Etanercept is a tumor necrosis factor (TNF) blocker that is … Continue reading
Posted in Cryonics, Health, Neuroscience
Tagged Alzheimer's Disease, Brain Aging, Dementia, Enbrel, Etanercept
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Selection bias and dietary supplements
One problem in assessing the merits of taking a specific dietary supplement (ranging from vitamins to exotic multi-ingredient compounds) is widespread selection bias in the documentation that is supposed to support the use of the supplement in question. The sheer … Continue reading
Living with children while practicing calorie restriction
“The only thing that retards aging is calorie restriction. As genetic studies go forward, we’ll find out why.” Roy Walford Our society in America currently as of 2008 has more overweight people than average-weight people. ‘Healthy weight’ Americans consist of … Continue reading
Posted in Health
Tagged Caloric Restriction, Child Rearing, Cryonics, Losing Weight, Obesity, Parenting, Shannon Vyff
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Shannon Vyff on teaching children about the future, caloric restriction, and cryonics
Over the next three days Shannon Vyff will be guest blogging for Depressed Metabolism. Shannon Vyff is a practicing caloric restrictionist, Alcor member, and Methuselah Foundation supporter. Shannon also volunteers for her local Unitarian Universalist Church and La Leche League … Continue reading
Posted in Cryonics, Health
Tagged 21st Century Kids, Caloric Restriction, Child Rearing, Cryonics, Parenting, Shannon Vyff, Transhumanism
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Wide therapeutic window for melatonin in stroke
Neuroprotective agents for stroke continue to fail in clinical trials. One important reason is that the therapeutic window for many of those agents is too narrow to confer benefits to acute stroke victims. It would be desirable to have a … Continue reading
Posted in Cryonics, Health, Neuroscience
Tagged Cerebral Ischemia, Cryonics, Melatonin, Stroke
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Iceland’s Blue Lagoon, skin aging and psoriasis
The practice of balneotherapy, also known as water treatment or spa therapy, has experienced a resurgence in popularity in recent years, especially amongst those with skin diseases such as psoriasis and atopic dermatitis. Salts, minerals, and bacteria particular to certain … Continue reading
Posted in Arts & Living, Health, Science
Tagged Aging, blue lagoon, iceland, Medical Tourism, psoriasis, skin care
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Combination therapy: The patient’s view
One consequence of the growing understanding of the biochemical pathways involved in brain injury resulting from cardiac arrest, stroke, and brain trauma is that there is an increasing consensus among researchers that combination therapy is the most logical treatment for … Continue reading
Posted in Cryonics, Health
Tagged Cancer, Cardiac Arrest, Drug Cocktail, NXY-059, Stroke
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