Depressed Metabolism

In 2005 the American heart association revised its standards for CPR increasing the number of compressions from 80 cpm to 100 cpm, eliminating pauses for ventilation, and urging that focus be shifted to compressions (perfusion) rather than ventilation. This latter change is more profound than it might seem at [...]

Alcor is having a Texas (TX) Readiness Team Training this July 25th and 26th.
This training is free and open to Cryonics Institute members as well.
July 25th 2009, 10:00am to 5:00pm, lunch provided at 1:00pm
July 26th 2009, 10:00am to 3:00pm, lunch provided at 1:00pm
All TX area cryoncists are encouraged to attend to learn more about the [...]

If conventional cardiopulmonary support (CPS) in cryonics is difficult to perform adequately, and impossible to sustain for more than brief periods (30-60 min) before exhausting even a 3-man standby team, this is even more the case for active compression-decompression CPS (ACD-CPS) using the ResQPump (formerly the Ambu CardioPump). Even in the conventional medical setting of [...]

Sometime in the 1780s the French scientist Jacques Charles’s noted that  at constant pressure, the volume of a given mass of an ideal gas increases or decreases by the same factor as its temperature on the absolute temperature scale. Or, put more simply, the gas expands as the temperature increases. This is known [...]

According to this news item the Alcor Life Extension Foundation is taking legal action against the brother and sister of an Alcor member who “denied the foundation’s request for his body and didn’t notify them of their brother’s death until months after he was buried.” Although some may question the wisdom of pursuing this case [...]

Source: ExtroBritannia
Why the much anticipated medical breakthroughs of the early 21st century are failing to materialize
Saturday 30th May 2009, 2pm-4pm. Room 403 (fourth floor), Birkbeck College, Torrington Square, London WC1E 7HX. There’s no charge to attend, and everyone is welcome.
Speaker
Mike Darwin has 30 years experience in cutting edge medical research. Co-founder of the Institute for [...]

David Wallace Croft is an Alcor member in the Dallas area where he lives with his wife Shannon and five children, Ada, Ben, Tom, Abe, and Ted.  He is employed as a Java software developer and is a part-time doctoral student.  His contact information and his weblog are available at www.CroftPress.com.

1. How did you first [...]

In “Ice Baby” by Tom Mueller, the May 2009 issue of National Geographic announces the recent discovery of a 40,000 year old baby mammoth in Sibera. She is called Lyuba, named after the wife of the Nenet reindeer herder who found her, and is in near-pristine condition, having even her eyelashes. In fact, besides most [...]

It is common medical knowledge that after 5 minutes of cardiac arrest the prospects of successful resuscitation without neurological impairment become progressively bleak. But there is less consensus on the mechanisms of such injury. One strong candidate is what is called the “no-reflow” phenomenon. No-reflow refers to the impairment of perfusion of the brain after [...]

At the hospital where Linda works, nurses and other employees swap many ‘helpful hints’ via email, and one of these ideas recently circulated seemed to be a technique cryonicists could use to increase the chances that their suspension organizations would find out quickly about their situations, in case of an emergency.
The way it works is [...]

In his article entitled ‘Evidence Based Cryonics’ Aschwin de Wolf unassailably argues that: “There is an urgent need to move from extrapolation based cryonics to evidence based cryonics. This will require a comprehensive research program aimed at creating realistic cryonics research models. It will also require vast improvements in the monitoring and evaluation of cryonics [...]

Basile J. Luyet (1897-1974) can be considered the father of modern cryobiology. His book “Life and Death at Low Temperatures” is a classic in the field and his journal “Biodynamica” evolved into a publication solely dedicated to the study of low temperature biology. Luyet identified the possibility of solidification without crystallization at low temperatures (vitrification) [...]

Cryonics patients can greatly benefit from rapid stabilization after pronouncement of legal death. One fortunate feature of stabilization procedures is that the most effective and validated procedures are relatively inexpensive and easy to perform.  The difference between no stabilization procedures at all and procedures that aim to rapidly restore blood circulation and drop the patient’s [...]

Under ideal circumstances cryonics patients are stabilized immediately after pronouncement of legal death by restoring  blood flow to the brain, lowering temperature, and administering medications. In most cryonics cases, however, there is a delay between pronouncement of legal death and start of cryonics procedures. In some cases there are no stabilization interventions at all. Provided [...]

I realized recently that this year marks the 40th anniversary of the first manned landing on the moon.
The irony strikes me, for the Apollo missions did not lead to any follow-up in manned space travel. Nobody anticipated that we’d send men to the moon just a few times to establish dominance over the Soviet Union [...]

The association of cryonics with “transhumanism” seems inevitable but is problematic.  It seems inevitable because cryonics should be most attractive to people with a very positive perspective on the future capabilities of technology. Barring rapid advances in mitigating aging, cryonics  offers the only credible option for transhumanists to become a part of that future. It [...]

Following the news that mice have been cloned from 16 year old frozen tissue comes an announcement that scientists have made advances in resurrecting  the extinct Pyrenean Ibex. This does not only offer hope that someday other extinct species may be resurrected and returned to nature, it further reinforces the power of low temperatures to [...]

When I was in New Zealand in 1999, CI Member Cam Christie told me that one of his co-workers was against cryonics because she was a Jehovah’s  Witness and her church had a position against cryonics. I recently found an article about cryonics on the Jehovah’s Witnesses website:
The piece contains the statement:
“…the use of nanotechnology [...]

For Immediate Release, Friday, 24 January, 2009
Date: 23 January, 2009
Introduction
I have been informed that Marcelon (Marce) Johnson died on 01/21/2009, was cremated, and not cryopreserved.
I understand this information may come as a surprise and as a disturbing shock to many people, especially those who loved and knew Marce, as I did. I thus feel [...]

The cryonics organizations Alcor and the Cryonics Institute have taken great care to correct some of the persistent myths about cryonics. With so much widespread misinformation being circulated in the media it seems trivial to pay attention to some of the misconceptions that some people who are sympathetic to cryonics hold. But the price of [...]

Patrick Millard is a Michigan based artist who works with different media including photography, painting, mixed media, sound, and installation. He currently works as an adjunct professor of photography at Grand Valley State University and Grand Rapids Community College and is a photography instructor at the Urban Institute for Contemporary Arts in Grand Rapids.
One of [...]

Robert J. White is most known, or perhaps most notorious, for his work on primate head transplants. Less known, but more relevant to the practice of human cryopreservation, is his work in cerebral ischemia, hypothermia, and brain preservation. Most of White’s innovative work was published in the 1960s and 1970s. White also published a substantial [...]

“Buddhism and Epicureanism combat the fear of death by accommodating the emotions to the reasonable certainty of death. Contemporary immortalism (which includes projects such as life extension, cryonic suspension, and universal immortalism) argues that scientific and technological solutions to the problem of death can be found, thus questioning the inevitability of death. Buddhist, Epicurean, and [...]

Esquire magazine features an article on scientist Mark Roth and his research into “suspended animation.” As the website title “The Mad Scientist Bringing Back the Dead…. Really” indicates, this is not supposed to be a detailed account of Ikaria’s recent advances in induction of depressed metabolism but a sensationalist piece on mad scientists. Although the [...]

One of the most neglected aspects of cryonics is that its procedures, and the research to support them, can have important practical applications in mainstream fields such as organ preservation and emergency medicine. Contrary to popular opinion, cryonics does not just involve an optimistic extrapolation of existing science but can set the standard for these [...]

Recent advances with the use of hydrogen sulfide, carbon monoxide and “hibernation induction triggers” to depress metabolism in animal models have  renewed interest  in the possibility of human hibernation.  The ability to drastically depress human metabolism without the use of cold (or in combination with cold) would have a number of important medical and scientific [...]

Japanese scientists have managed to clone a mouse that had been frozen without any cryoprotection for 16 years at minus 20 degrees Celsius. The researchers used the researchers used brain cell nuclei, and planted it into an egg of another living mouse, leading to the birth of the cloned mouse.
Although the objective of cryonics is [...]

This is the second in a series of interviews with individuals in the life extension and cryonics movement. The first interview was with Cryonics Institute president Ben Best. This interview is with Regina Pancake, Alcor’s Readiness Coordinator.
How did you get involved in cryonics?
My story is not your typical in the details, but in the overall [...]

My experiences with death began in 1974, when I was age 10.
On Labor Day Sunday, while watching the Jerry Lewis MDA telethon, my father told me to turn the TV off.
When I asked why, he said my grandfather, age 74, died.
I would learn years later that he had emphysema and heart trouble.
I did not know [...]

It has been shown that perfusability of the brain is significantly compromised after long-term (>5 min) ischemic events (the “no reflow” phenomenon). Improving cerebral blood flow after circulatory arrest is one of the fundamental objectives of human cryopreservation stabilization protocol.  To that end, cryonics organizations administer the resuscitation fluid Dextran-40 and the drug Streptokinase to [...]

Unless you are a long-time cryonicist or a surgeon, you may not have heard of BioTime before. This company, recently profiled for its innovative stem cell research in Life Extension Magazine, is best known for producing the blood-volume expander Hextend, which was initially developed by Trans Time, an early cryonics company performing ultra-profound hypothermia research. [...]