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Recent Posts
- Annotated bibliography of cryoprotectant toxicity
- The 2011 Calorie Restriction Society Conference
- Fifth SENS Conference
- What you don’t eat can’t hurt you
- Steve Jobs’ morbid glorification of death
- Smartphone Apps for the Smart Cryonicist
- Personalized Cryonics
- Intermediate temperature storage in cryonics
- Alcor member profile of Aschwin de Wolf
- The 2011 Cryobiology Conference
Cryonics Magazine- Scientists Eavesdrop Inside the Mind
- Discovery May Provide Insight into Brain Cell Aging
- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
Fight Aging!
Chronosphere- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Resources
- 21st Century Medicine
- Alcor Life Extension Foundation
- Alcor News
- Ben Best’s Cryonics Page
- Brain Preservation Foundation
- Chronosphere
- Cryonics Institute
- Cryonics Magazine
- Cryonics Northwest
- FDAReview
- Fight Aging!
- Forever For All
- Future of Humanity Institute
- Institute for Molecular Manufacturing
- Nanomedicine
- Programmed Aging
- Safar Center for Resuscitation Research
- SENS Foundation
- Society for Cryobiology
- Soft Machines
- Suspended Animation
- Synthetic Biology
- Water in Biology
Meta
Author Archives: Mike Darwin
The RhinoChill: A New Way to Cool the Brain Quickly
We scientists are difficult, cranky, and above all, maddeningly frustrating people. Want to turn lead into gold? No problem, we can tell you how to do that, and in fact have even done it already: the only catch is that … Continue reading
Posted in Neuroscience, Science
Tagged Cooling, Cryonics, Hypothermia, Ischemia, Mike Darwin, Neuroprotection, RhinoChill
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Prospects for Mild Therapeutic Hypothermia and Improved CPR in Cardiopulmonary Cerebral Resuscitation
There are two kinds of hypothermia: protective or preservative hypothermia, and therapeutic hypothermia. The former is easy and straightforward to understand for most, clinicians and laymen, alike. However, therapeutic hypothermia has proved to be a far more difficult idea to … Continue reading
Posted in Neuroscience, Science
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At last, a sure-cold way to sell cryonics with guaranteed success!
A humorous romp through a promising new technique in aesthetic medicine from one cryonicist’s (warped) point of view. Figure 1: Before cryopreservation (L) and after cryopreservation (R). As everyone involved in cryonics for more than a fortnight is sadly aware, … Continue reading
Posted in Cryonics, Health, Science
Tagged Adipocytes, Chilling Injury, Cosmetic Surgery, Cryobiology, Cryolipolysis, Cryonics, Hypothermia, Mike Darwin, Organ Preservation, Zeltiq
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CPR: A pair of hands aren’t enough
CPR: A Pair of Hands Aren’t Enough: You Also Need a Heart and a Brain “Anyone, anywhere, can now initiate cardiac resuscitation procedures. All that is needed are two hands.” [Kouwenhoven WB, Jude J, Knickerbocker G. Closed chest cardiac massage. … Continue reading
CPR and the breath of death?
And the Lord God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul. Genesis 2:7 For breath is life, and if you breathe well you will … Continue reading
Posted in Cryonics, Health, Science
Tagged Active Compression Decompression CPR, Autopulse, CPR, Cryonics, LUCAS, LUCAS 2, Mechanical CPR, Michigan Thumper, Mike Darwin, Negative Pressure Ventilation
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CPR: new standards; new needs
In 2005 the American heart association revised its standards for CPR increasing the number of compressions from 80 cpm to 100 cpm, eliminating pauses for ventilation, and urging that focus be shifted to compressions (perfusion) rather than ventilation. This latter … Continue reading
ACD-CPR & the rise of the machine?
If conventional cardiopulmonary support (CPS) in cryonics is difficult to perform adequately, and impossible to sustain for more than brief periods (30-60 min) before exhausting even a 3-man standby team, this is even more the case for active compression-decompression CPS … Continue reading
Posted in Cryonics
Tagged Active Compression Decompression CPR, Autopulse, CPR, CPS, Cryonics, Impedance Threshold Device, Impedance Valve, LUCAS 2, Mike Darwin, ResQPOD, ResQPump, Suspended Animation
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Two useful new respiratory products
Sometime in the 1780s the French scientist Jacques Charles’s noted that at constant pressure, the volume of a given mass of an ideal gas increases or decreases by the same factor as its temperature on the absolute temperature scale. Or, put … Continue reading
Posted in Cryonics
Tagged Charles' Law, Cryonics, End Tidal CO2, Endotracheal Tube, ETCO2, Jacques Charles, PressureEasy Cuff Pressure Monitor, Ultraprofound Hypothermia
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Response to Aschwin de Wolf’s ‘Evidence Based Cryonics’
In his article entitled ‘Evidence Based Cryonics’ Aschwin de Wolf unassailably argues that: “There is an urgent need to move from extrapolation based cryonics to evidence based cryonics. This will require a comprehensive research program aimed at creating realistic cryonics … Continue reading
Posted in Cryonics
Tagged Aschwin de Wolf, Cryonics, Evidence Based Cryonics, Evidence Based Medicine, Hypothermia, Medications, Mike Darwin, Neuroprotection
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Marcelon Johnson dies and is not cryopreserved
For Immediate Release, Friday, 24 January, 2009 Date: 23 January, 2009 Introduction I have been informed that Marcelon (Marce) Johnson died on 01/21/2009, was cremated, and not cryopreserved. I understand this information may come as a surprise and as a … Continue reading
Time for the rebirth of cryonics in Britain
A PDF file of this article with images is available here. “Tenderly you stroke a Nettle, and it stings you for your pains. Grasp it like a man of mettle, and it soft as silk remains.” – Old English proverb … Continue reading
D(+)-Lactose and other sugars in organ preservation and cryonics
A PDF file of this document is available with images and structural visualization of various sugars. D(+) lactose monohydrate is the principal sugar in mammalian milks. The monohydrate part is easiest to explain; it simply means that the lactose molecule … Continue reading
Posted in Cryonics, Science
Tagged Chemistry, Cryonics, Hypothermia, Mike Darwin, Organ Preservation, Organic Chemistry, Sugars
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Structure-function analysis of neuroprotectants
In “The chemistry of neuroprotection”, the author argues convincingly that there could be great benefit from a systematic and rigorously scientific study of the physical chemistry of putative neuroprotectants vis-à-vis their pharmacological effect. However, the first example used of the … Continue reading
Posted in Cryonics, Neuroscience, Science
Tagged Cerebral Ischemia, Chemistry, Clinical Trials, Drugs, Neuroprotection
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