Cryonics Magazine- Scientists Eavesdrop Inside the Mind
- Discovery May Provide Insight into Brain Cell Aging
- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
- Fight Aging!
- Chronosphere
- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Author Archives: Chana de Wolf
Smartphone Apps for the Smart Cryonicist
As every modern consumer knows, smartphones are today’s go-to portable technology. Everything from GPS navigation to finding a good deal on your next meal or haircut right NOW to a wide variety of games and applications may be had at … Continue reading
Posted in Cryonics, Health
Tagged apps, Cryonics, Health, mobile technology, smartphone
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Interview with Alcor member David Croft
David Wallace Croft is an Alcor member in the Dallas area where he lives with his wife Shannon and five children, Ada, Ben, Tom, Abe, and Ted. He is employed as a Java software developer and is a part-time doctoral … Continue reading
Posted in Cryonics, Society
Tagged Alcor, Cryonics, David Croft, Interview, Universal Immortalism
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40,000 year old frozen baby mammoth unearthed
In “Ice Baby” by Tom Mueller, the May 2009 issue of National Geographic announces the recent discovery of a 40,000 year old baby mammoth in Sibera. She is called Lyuba, named after the wife of the Nenet reindeer herder who … Continue reading
Posted in Cryonics, Science
Tagged Baby Mammoth, Cloning, Cryonics, DNA, Mammoth, National Geographic, Siberia
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A simple method to resuscitate rats from cold circulatory arrest
This is the eighth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. In 1982, P.D. Rogers and G.P. Webb published some of their observations (based on previous papers and … Continue reading
Posted in Death, Health, Neuroscience, Science
Tagged Audrey Smith, Death, Hypothermia, Hypoxia, Radoslav Andjus, Ultra-Profound Hypothermia
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Resusciation of larger mammals from subzero temperatures
This is the seventh entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. After spending a few years on perfecting on Andjus’ technique for resuscitating rodents (rats and hamsters) from … Continue reading
Posted in Death, Science
Tagged Audrey Smith, Death, Freezing, Science, Ultraprofound Hypothermia
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Behavioral effects of ultraprofound hypothermia in rats
This is the sixth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. After successfully reanimating rats from deep body temperatures of 0 – 2 degrees C and subsequent respiratory … Continue reading
Posted in Death, Science
Tagged Death, Learning, Memory, N. Mrosovsky, Science, Ultraprofound Hypothermia
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Methods to resuscitate rodents from ultraprofound hypothermia
This is the fifth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. As we have seen, Radoslav Andjus had determined a method for achieving excellent (75-100%) recovery rates in … Continue reading
Posted in Death, Science
Tagged Audrey Smith, Death, S.A. Goldzveig, Science, Ultraprofound Hypothermia
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Resuscitation of rats from high subzero temperatures
This is the fourth entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. Up to this point we have discussed the groundbreaking research in the early 1950s performed by Radoslav … Continue reading
Posted in Death, Science
Tagged Audrey Smith, Death, Radoslav Andjus, Science, Ultraprofound Hypothermia
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Microwave diathermy to resuscitate hypothermic rats
This is the third entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. Andjus and Smith were delighted that they had managed to modify Andjus’ chest-wall heating technique from using … Continue reading
Posted in Death, Science
Tagged Death, James Lovelock, Radoslav Andjus, Science, Ultraprofound Hypothermia
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Improved methods for resuscitation of cold rats
This is the second entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. As discussed previously, in 1951 Radoslav Andjus developed a simple method for resuscitating rats cooled to deep … Continue reading
Posted in Death, Science
Tagged Audrey Smith, Death, Radoslav Andjus, Science, Ultraprofound Hypothermia
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Resuscitation of rodents from hypothermic circulatory arrest
This is the first entry in a series about resuscitation of non-hibernating rodents from circulatory arrest at ultraprofound hypothermic and high subzero temperatures. Prior work in hypothermia began in the early 1900s, but because cardiac and respiratory arrest were observed … Continue reading
Posted in Death, Science
Tagged Audrey Smith, Death, Radoslav Andjus, Science, Ultraprofound Hypothermia
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Robert Freitas discusses the future of nanomedicine
Nanotechnology idea-man Robert Freitas, Jr. has published an article in the January 2009 issue of Life Extension Magazine providing a tutorial in nanomedicine and documenting its progression toward real-world application. In “Nanotechnology and Radically Extended Life Span,” Freitas describes several … Continue reading
Greg Jordan on Buddhism, Epicureanism, and Immortalism
“Buddhism and Epicureanism combat the fear of death by accommodating the emotions to the reasonable certainty of death. Contemporary immortalism (which includes projects such as life extension, cryonic suspension, and universal immortalism) argues that scientific and technological solutions to the … Continue reading
Posted in Cryonics, Death
Tagged Buddhism, Cryonics, Death; Fear of Death, Epicureanism, Immortalism, Life Extension, Universal Immortalism
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Nanotechnology: The message matters
A recently conducted study brings a warning to technophiles who think that the facts are all that matter when informing a group of people about a new technology. The fact of the matter is that the message matters more. In … Continue reading
Gender differences in stroke treatment and prevention
Over the years, experimental science has developed a standard protocol for the testing of medical hypotheses using animal models which calls for the use of males only. Why? Because no laboratory scientist wants to deal with those pesky female hormones. … Continue reading
Lindbergh and Carrel’s quest to live forever
It’s difficult to follow up a best-selling book about the cultural history of the penis, but David M. Friedman has a knack for engaging readers in topics that others find difficult to broach. This time he tackles the touchy subject … Continue reading
Posted in Death, Science
Tagged Alexis Carrel, Charles Lindbergh, Immortality, Isolatonism, Perfusion, Science
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Promoting cerebral blood flow in cryonics patients
It has been shown that perfusability of the brain is significantly compromised after long-term (>5 min) ischemic events (the “no reflow” phenomenon). Improving cerebral blood flow after circulatory arrest is one of the fundamental objectives of human cryopreservation stabilization protocol. … Continue reading
Posted in Cryonics, Neuroscience
Tagged Blood Clotting, Cerebral Blood Flow, Cerebral Ischemia, Cryonics, Dextran-40, Medications, Neuroscience, Streptokinase
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BioTime’s quest to defeat aging
Unless you are a long-time cryonicist or a surgeon, you may not have heard of BioTime before. This company, recently profiled for its innovative stem cell research in Life Extension Magazine, is best known for producing the blood-volume expander Hextend, … Continue reading
PLAC blood test for sudden cardiac arrest and stroke risk
Life Extension Foundation (LEF) unveiled a new blood test in an article in this month’s Life Extension Magazine (November 2008). Unlike cholesterol testing, which simply gives a measurement of high-density (HDL) and low-density (LDL) lipoprotein levels and provides little information … Continue reading
Posted in Health, Science
Tagged Blood Testing, Cardiac Arrest, Health, Ischemia, Life Extension Foundation, PLAC, Science
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No disease in the brain of a 115-year old woman
In August 2008, Neurobiology of Aging published the interesting observations of den Dunnen, et al. of the post-mortem body of a 115 year old woman, which showed no evidence of atherosclerosis. Her brain was devoid of the amyloid plaques characteristic … Continue reading
Revitalize aging feet
My mother, being a decidedly well put-together woman, impressed upon me the importance of self-care from an early age. She was obsessed with skin maintenance and especially careful to instruct me in hand and foot care. I was given my first bottle … Continue reading
Posted in Health
Tagged Eucalyptus, Flat Feet, Foot care, Health, Life Extension Foundation
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Recent developments in the treatment of Alzheimer’s
The full text of the Life Extension Foundation magazine article (August 2008) describing the use of Enbrel for the treatment of Alzheimer’s disease and announcing LEF’s new Enbrel trial, is now available. As previously discussed, Enbrel (entanercept) has been shown … Continue reading
Posted in Health, Neuroscience
Tagged Aging, Alzheimer's Disease, Drugs, Life Extension Foundation
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TNF-alpha modulation in Alzheimer’s patients
More than a decade of basic research and clinical evidence now implicates inflammatory processes in the pathogenesis of Alzheimer’s disease (AD). TNF-alpha is a pro-inflammatory cytokine, also known as the “master regulator” of the immune response, and is the key … Continue reading
Gary Taubes and bias in nutrition science
In a recent blog post, Overcoming Bias reports that Gary Taubes, who has written much to further the idea that refined carbohydrates are a stronger contributing factor to overweight and “diseases of civilization” than dietary fat and cholesterol, has compiled … Continue reading
Insurance against death through cryonics
Let’s face it: we’re all (still) getting older, and aging leads to death. This is a major reason for cryonics’ existence — to preserve ourselves, usually in an aged, diseased, and/or deteriorated state, until medical science is capable of curing … Continue reading
Cerebral blood flow during and after cardiac arrest
As discussed in a previous post, perfusion of the brain following long-term (>5 min) ischemia has been shown to be significantly compromised, particularly in subcortical regions. An interesting recent article by Ristagno, et. al in Resuscitation (May 2008) has added … Continue reading
Posted in Neuroscience, Science
Tagged Blood Pressure, Brain, Cardiac Arrest, Chest Compressions, CPR, Cryonics, Ischemia, Resuscitation
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Soft nanotechnology
Ever since humans imagined the ability to deliberately manipulate matter on the atomic scale, they have glimpsed the boundless possibilities of the science of nanotechnology. And for almost as long, they have disputed whether molecular machines should be built using … Continue reading
Posted in Cryonics, Science
Tagged Eric Drexler, Nanotechnology, Richard Jones, Synthetic Biology
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Cerebral ischemia and impairment of circulation
Cryopreservation of the brain depends on the removal of blood from the brain’s vasculature and its replacement with cryoprotective solutions in order to prevent ice crystal formation (freezing) during cooling (i.e., facilitate vitrification). Ultimately, the success of a good cryoprotectant … Continue reading
Posted in Cryonics, Neuroscience
Tagged Blood Coagulation, Cardiac Arrest, Cryonics, Heparin, Stroke
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Will POLST integrate end-of-life care options?
A recent investigation (PDF) of state statutes and legislation affecting the ability to implement a nation-wide program to standardize medical orders reflecting individual patients’ end-of-life treatment preferences was made publicly available by Oregon Health & Science University. The POLST (Physician … Continue reading
HealthHaven interview with Chana de Wolf now online
Now online is a radio interview with Depressed Metabolism writer Chana de Wolf on cryonics. Some of the issues that are discussed include the use of cryonics for preventing vegetative patients, and the question why cryonics has remained so unpopular … Continue reading
Chana de Wolf on HealthHaven radio show
Please join Chana de Wolf as she speaks with Alcor member Larry McElhinney on his daily HealthHaven live webcast this Friday, June 13, 2008, at 12:00 p.m. PST. Chana and Larry will discuss cryonics and the science of life extension, … Continue reading
Intranasal administration of medications
Experiments investigating the effects of medication administration via the nose are becoming increasingly common in scientific literature. Direct olfactory transport to the brain and the consequent lack of systemic side effects make nasal administration of neuroactive drugs a very attractive … Continue reading
Wide therapeutic window for melatonin in stroke
Neuroprotective agents for stroke continue to fail in clinical trials. One important reason is that the therapeutic window for many of those agents is too narrow to confer benefits to acute stroke victims. It would be desirable to have a … Continue reading
Posted in Cryonics, Health, Neuroscience
Tagged Cerebral Ischemia, Cryonics, Melatonin, Stroke
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Ev Cooper’s cryonics classic published online
Few, if any, cryonicists today can retrace their personal interest in cryonics to Evan Cooper. Despite the broader recognition of Robert Ettinger’s book, “The Prospect of Immortality,” which was commercially published in 1964, Cooper’s privately published 1962 manuscript, “Immortality: Physically, … Continue reading
Posted in Cryonics, Death
Tagged Cryonics, Ev Cooper, Immortality, Nathan Dhuring, Singularity, Society For Venturism, Transhumanism
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Iceland’s Blue Lagoon, skin aging and psoriasis
The practice of balneotherapy, also known as water treatment or spa therapy, has experienced a resurgence in popularity in recent years, especially amongst those with skin diseases such as psoriasis and atopic dermatitis. Salts, minerals, and bacteria particular to certain … Continue reading
Posted in Arts & Living, Health, Science
Tagged Aging, blue lagoon, iceland, Medical Tourism, psoriasis, skin care
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