Cryonics Magazine- New Evidence Keeping Brain Sharp and Active Wards off Alzheimer’s
- New Discoveries in Cell Aging
- Eye Trials Give Hope for Stem Cells
- How Stem Cell Implants Help Heal Traumatic Brain Injury
- Victory For Crowdsourced Biomolecule Design
- New Approach to Preventing Fatal Septic Shock
- Alzheimer’s Damage Occurs Early
- Oxidative DNA Damage Repair
- Messenger RNA Self-destruct Mechanism Revealed
- How the Brain Cell Works: A Dive Into Its Inner Network
- Fight Aging!
- Chronosphere
- Cryonics “Castle”
- Doing the Time Warp
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 3
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 2
- Interventive Gerontology 1.0.02: First, Try to Make it to the Mean: Diet as a life extending tool, Part 1.
- Fortune and Men’s Eyes
- Interventive Gerontology 101.01: The Basics
- The Kurzwild Man in the Night
- Fucked.
- You Bet Your Life!
Monthly Archives: September 2007
Leukocytes and cerebral ischemia
In their paper “The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct?” D.F. Emerich et al. review the literature on the involvement of neutrophils in cerebral ischemia: “We reasoned that if neutrophils play an … Continue reading
Posted in Cryonics, Neuroscience
Tagged Inflammation, Leukocytes, Necrosis, Neutrophils, Stroke
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Characterization of afterhyperpolarization (AHP) in cryopreserved brain slices
An ongoing quest in cryonics is the successful demonstration of memory sustainment after cryopreservation of the brain and rewarming from cryogenic temperatures. To that end, landmark experiments were performed by Pichugin, et al. (2006) on rat hippocampal brain slices which … Continue reading
Posted in Cryonics, Neuroscience
Tagged Brain, Brain Slice, Cryobiology, Hippocampus, Memory, Viability
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Whole body cryopreservation with preferential brain treatment
A strong argument in favor of neuropreservation is that all efforts can be devoted to vitrification of the brain. Perfusion times are shorter and challenges present during perfusion of the rest of the body (such as abdominal swelling and the … Continue reading
Intranasal administration of vasoactive agents
Stabilization in cryonics requires immediate administration of vasoactive medications to maintain blood pressure, thereby assisting and enabling adequate perfusion during cardiopulmonary support. Traditionally, vasopressors such as epinephrine have been administered intravenously, requiring skilled technicians to establish an IV line as … Continue reading
Load distributing band CPS
The Autopulse presents an alternative to the (high impulse) active compression-decompression devices that cryonics organizations currently employ to provide cardiopulmonary support (CPS) during stabilization. The Autopulse uses batteries instead of compressed oxygen and is easy to set up and operate. … Continue reading
Rapid stabilization in human cryopreservation
“Even in the case of advanced Alzheimer’s disease, a person is ultimately not declared dead because of the loss of personhood, but as a consequence of secondary whole brain death or cardiac and respiratory arrest. In essence, today’s medicine routinely … Continue reading
Energy metabolism and sepsis
In this recent paper the authors argue that “multi-organ failure secondary to sepsis may actually represent an adaptive hypometabolic response to preserve ATP homeostasis in the face of a prolonged inflammatory insult.” Unlike organ specific diseases, mitochondrial dysfunction in multiple … Continue reading